Evaluation of DNA Damage Using Microwave Dielectric Absorption Spectroscopy

نویسندگان

  • Makoto Hirayama
  • Youichirou Matuo
  • Takeyoshi Sunagawa
  • Yoshinobu Izumi
چکیده

Background: Evaluation of deoxyribonucleic acid (DNA)-strand break is important to elucidate the biological effect of ionizing radiations. The conventional methods for DNA-strand break evaluation have been achieved by Agarose gel electrophoresis and others using an electrical property of DNAs. Such kinds of DNA-strand break evaluation systems can estimate DNAstrand break, according to a molecular weight of DNAs. However, the conventional method needs pre-treatment of the sample and a relatively long period for analysis. They do not have enough sensitivity to detect the strand break products in the low-dose region.

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تاریخ انتشار 2017